Melatonin in combination with vitamin D has also been shown to protect against apoptotic ischemia-reperfusion injury in the kidney.24. FDA Makes Narcan Available Over the Counter - articles.mercola.com In rat models of sepsis, melatonin reduces oxidative damage and organ dysfunction and also decreases mortality. Mitochondrial dysfunction has been related to the etiologies of many complex diseases where overactivation of the renin-angiotensin-aldosterone system (RAAS), vitamin D deficiency and the reduction of melatonin synthesis converge. It's been shown to play a role in viral, bacterial and fungal infections14and as early as June 2020, researchers suggested it might be an important adjunct to COVID-19 treatment.15,16,17According to the authors of that paper, melatonin attenuates several pathological features of COVID-19, including:18. The letter to Mercola was among nearly 80 the FDA has posted since Feb. 1. For example, some drugs can signal changes in the brain that, over time, make it difficult to stop . Your master biological clock resides in the suprachiasmatic nucleus of your brain (SCN), which is part of your hypothalamus. In scientific studies, melatonin has been shown to increase sleepiness, help you fall asleep more quickly and stay asleep, decrease restlessness, and reverse daytime fatigue. Melatonin is not recommended for infants or toddlers under 5 years old. There is no established maximum safe dose of melatonin. Most melatonin supplements dont allow you to choose your level of melatonin. Sleep Support is not appropriate for children, and we only recommend it for occasional use by adults 18 years and older. A paper14 published in the May 2020 issue of The Journal of Steroid Biochemistry and Molecular Biology which I was able to review early, parts of which I'm sharing with you here sheds further light on this connection. The results,18 which were published in conjunction with the 2014 American Society of Clinical Oncology Meeting, found a tumor response in just over 29 percent of those receiving melatonin at night, compared to just under 8 percent of those receiving it in the morning, and 10.5 percent of placebo recipients. As an added bonus, you can support your immune health at the same time.*. Would you like to see an improvement in the quality of your sleep such as getting more deep sleep? Melatonin Significantly Reduces Covid-19 Mortality - Dr Joseph Mercola | LewRockwell.com Melatonin is a hormone synthesized in your pineal gland and several other organs,1 indeed in most cells, including human lung monocytes and macrophages, as it is actually synthesized in your mitochondria.2 How to Detox Spike Protein from Body - Dr Mercola - OneDayMD At the end I've added links to an HBN radio interview on melatonin, a book, an article and some bullet points from a trade publication covering melatonin myths While most well-known as a natural sleep regulator, melatonin also has many other important functions.
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