This feels like it could go either way, but the edge goes to the home team. If the Jaguars have the same kind of issues along the defensive front they did last week, it'll be another long day. Vikings 20, Bears 17 -- Courtney Cronin, The Bears are 14-2 in their past 16 home games against the Vikings dating back to the 2001 season. Panthers 24, Lions 21 -- David Newton, Defending Newton will be tough, and linebacker Luke Kuechly could cause Stafford some issues, but the Lions have shown they are one of the better teams in the NFC. And regardless of whos at quarterback, Adam Thielen and Stefon Diggs need to spark the Vikings' aerial attack early while the running game gets in its groove with Latavius Murray taking the reins for an injured Dalvin Cook. NFL Week 5 Early Odds, Picks & Predictions (2022) by Jason Radowitz | Sep, 29 2022 Before Week 4 begins, there's plenty of value with some Week 5 lines. Trotter's pick: Browns 20, 49ers 16 More NFL coverage , Bold prediction: The Bucs will hold Alvin Kamara under 100 all-purpose yards and under 45 rushing yards. The Bengals can build on their momentum here, and a win would make them 2-3 prior to their bye. When the draft ended, there was a total of 43 trades, breaking . It's all here to help get you ready for a loaded weekend of NFL football. Wentz's seven picks are the most in the NFL. Russell Wilson's QBR in five road games against the Rams is 48.6 compared with 71.5 in his 37 other road games. Matchup rating: 53.8 | Spread: TEN -3 (38.5), What to watch for: Marcus Mariota has not thrown an interception this season, but the Bills are tied with the Giants and 49ers for second in the NFL with five picks each. Stat to know: The Eagles' Carson Wentz has 963 passing yards on the season, and he needs 400 more to have his most through the first five games of a season in his career (his single-game career high is 364). They have an NFL-best plus-eight turnover margin. -- Michael Rothstein. But its not like Rodgers needs time to get ready to face a Rod Marinelli-coached defense. FPI prediction: CHI, 63.5% (by an average of 4.8 points), Matchup must-reads: Mack expected to be with the Raiders 'for the long haul' Daniel embraces seldom-used, uncertain backup QB life Roquan Smith says he's playing Sunday Carr: Burfict's 'heart is broken;' QB says ban isn't fair, 1 p.m. The Bills aren't known for a traditional ground game, but the Steelers' defense is giving up an average of 131.5 rushing yards per game. Dolphins 17, Titans 14 -- James Walker, The Chargers finished 1-3 on trips to the East Coast last season and are in the midst of a nine-game losing streak. That would help against a Lions offensive line featuring three solid first-round picks in left tackle Taylor Decker (2016), center Frank Ragnow (2018) and right tackle Penei Sewell (2021). Levis opens up about draft day Meanwhile, Mahomes has thrown two interceptions, and the team has also lost two fumbles through four games. Read more. Quarterback Jacoby Brissett has led the Colts to more than 30 points in a game only once in 19 starts, and that was 31 points in his second start back in Week 3 of the 2017 season. That number is down to once every 34.8 passes this season, and he ranks as QB23 through Week 4. However, Arizona's primary hope for winning this game lies with its run defense. NFL Expert Picks, Predictions, Lines: Week 5 - College Football News The Bills' offense -- which has gone three-and-out on 48 percent of drives this season, second most in the NFL -- will be playing short-handed at wide receiver because of a thumb injury to No. Williams' pick: Chargers 27, Broncos 20 See Week 5 rankings. With the return of Michael Gallup, Lamb will have chances to get away from Jalen Ramsey to make more plays. Keim's pick: Patriots 27, Redskins 7 Full schedule | Standings Tyrod Taylor has excelled in passing to Charles Clay and LeSean McCoy this season, but the Bengals boast the NFL's lowest yards per catch (6.49) by opposing tight ends and running backs. Baltimore's defense has struggled, and the amount of damage opposing teams have done through the air bodes well for the Bengals and Chase, who has received extra attention from opposing teams this season. Facebook; Twitter; Facebook Messenger; Pinterest; Email; Scoring is up across the NFL. Commanders WR Curtis Samuel has 26 receptions this season, tied with Travis Kelce and Davante Adams for eighth most in the NFL. He started slow, but has run for 199 yards combined the past two weeks and ranks third in the NFL in yards after first contact at 3.21 in that time. Texas has had 357 players selected in the NFL Draft. Read more. ET | Fox 2023 NFL mock draft: Todd McShay's final first-round predictions - ESPN